Searchable abstracts of presentations at key conferences in endocrinology

Endocrine Abstracts

Published by BioScientifica

Page 1 of about 1 results

ea0020p668 | Steroid Receptors | ECE2009

Increased fat mass in androgen receptor knockout mice is caused by decreased physical activity with no change in food consumption

Zajac Jeffrey , Rana K , Fam B , Andrikopoulos S , MacLean Helen

We have used an androgen receptor knockout (ARKO) mouse model with an in-frame deletion of the 2nd zinc finger of the DNA binding domain, which abolishes the genomic actions of the AR to investigate androgen regulation of fat mass. At 12 weeks of age, ARKO males have increased adiposity compared to wildtype (WT) males, with subcutaneous fat mass increased by 75% (P<0.001, n≥17/group) and infrarenal fat mass increased by 36% (P<0.05, n&...
0 shares

Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 | Privacy policy | Cookie settings

BiosciAbstracts

Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.

Find out more